Yes, technically driverless vehicles are possible, but not physiologically. In the 1960s futurists were predicting that within 20 years everyone would have their own flying car just like the Jetsons. Haven’t seen too many of those yet.

The two main reasons driverless cars are impractical is because of the need for humans to feel that flesh and blood is in control and to have someone to personally blame when things go bump. It’s the same reason that robots will always have their limitations — hardware isn’t human no matter how sophisticated.